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Adults apply a small amount as a thin layer on the affected area(s) twice daily or as directed by a doctor. If no improvement is seen after three months of treatment, use of this product should be discontinued. Other information: this product is not for use in the prevention of sunburn. Lightening effect of this product may not be noticeable when used on very dark skin. Sun exposure should be limited by using a sunscreen agent, a sun blocking agent or protective clothing to cover bleached skin after treatment is completed to prevent darkening from reoccurring.